Related Experiment Video
Updated: Aug 6, 2026
Standardized Histomorphometric Evaluation of Osteoarthritis in a Surgical Mouse Model
Published on: May 6, 2020
[Functional indices in assessment of gonarthrosis treatment efficacy with structum and chondrolon]
Material And Methods:
The trial included 50 patients aged from 40 to 67 years with osteoarthrosis (OA) stage I and II by Kellgren-Lawrence. Patients of group 1 (n=30) received chondrolon, of group 2 (n=20)--structum. Treatment efficacy was assessed by WOMAC scale, Leken's functional index, VAS pain at rest, walking, goniometry findings, time of 30 m walking.
Results:
A positive clinical effect was achieved in both groups by all the indices. The improvement was significant in VAS pain, functional tests, Leken's index, WOMAC scale. A positive trend in clinical symptoms and tests developed more quickly in the treatment with chondrolon than with structum (in 8 vs. 12 months, respectively). Treatment with different chondroitin sulphate drugs raised quality of life in gonarthrosis patients assessed by WOMAC scale, the effect being comparable.
Conclusion:
Structum and chondrolon can be used for OA stage I-II with moderate dysfunction of knee joints. The treatment course should be long, at least 3 months, 3-6 months for structum.
