[Menetrier's hypertrophic gastritis associated with polyarteritis nodosa]

Case presentation of a 61 year old male who presented with a 3 months' history of anorexia, weight loss, prolonged febrile syndrome, myalgias, peripheral polyneuropathy, abdominal pain, anemia, renal insufficiency, sonographically detected splenomegaly, elevated alkaline phosphatase, hypoproteinemia, sudden drops of the hematocrit, gastric ulcer with negative biopsies for malignancy and where the histological study of the surgical specimen confirmed the diagnosis of Ménétrier's disease or hypertrophic gastritis associated with nodose polyarteritis. The first explains the hypoproteinemia, edema; whereas the second explains the renal insufficiency, peripheral polyneuropathy, fever, skeletal muscle, spleen and liver involvements. The gastric ulcer, blood loss, anorexia, weight loss and abdominal pain can be justified by both diseases. We have been unable to find in the literature any other case of a similar association.