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[Treatment of non tuberculous mycobacteriosis with quinolones]
G Kevorkoff1, Z Micheli, D R Nigro
1Cátedra de Medicina II. U.N.C. Unidad Hospitalaria N. 5 Hosp. Tránsito Cáceres de Allende, Buchardo, Córdoba.
Abstract:
Two cases of Non-tuberculous Mycobacterium from the MAI group and another by Mycobacterium Fortuitum are presented. None of them with extrapulmonary manifestations. They were treated with a scheme of four drugs among which the Quinolone was included. The patients were adults with pulmonary processes clinically and radiologically similar to pulmonary Tuberculosis (TBC); non-tuberculous mycobacteria were isolated from the sputum. It has been shown "in vitro" that the nontuberculous mycobacteria are sensitive to the Fluoroquinolones. Thus, Ciprofloxacine or Ofloxacine were used, taking into consideration the initial polirresistence to the habitual tuberculostatics. Consequently, these patients were treated with schemes which included these new Quinolones, getting good clinical responsiveness and negativization of the sputum in all the cases.