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Analytical Techniques for Assaying Nitric Oxide Bioactivity
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Histochemical study of the nitric oxide synthase activity in experimental trichinellosis

E Hadaś1, L Gustowska, K Boczoń

  • 1Department of Biology and Medical Parasitology, Karol Marcinkowski University of Medical Sciences in Poznań.

Wiadomosci Parazytologiczne
|August 4, 2006
PubMed

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Nitric oxide (NO), an inorganic gas, acts as a potent second messenger in most animal and plant tissues. NO diffuses out of the cells that produce it and enters the neighboring cells to generate a downstream response. NO synthase (NOS) catalyzes NO production by the deamination of the amino acid arginine. There are three isoforms of NOS. Endothelial cells have endothelial NOS (eNOS), nerve and muscle cells have neuronal NOS (nNOS), and macrophages produce inducible NOS (iNOS) upon exposure to...