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Updated: Aug 6, 2026

Dual-Dye Optical Mapping of Hearts from RyR2R2474S Knock-In Mice of Catecholaminergic Polymorphic Ventricular Tachycardia
Published on: December 22, 2023
Idiopathic polymorphic ventricular tachycardia with normal QT interval in a structurally normal heart
Bassam K Mechleb1, Tariq Z Haddadin, Said B Iskandar
1Division of Cardiology, Department of Internal Medicine, James H. Quillen College of Medicine, East Tennessee State University, James H. Quillen VAMC, Johnson City, TN, USA. b_mechleb@hotmail.com
Abstract:
Polymorphic ventricular tachycardia (PVT) is a life-threatening arrhythmia that is typically related to long QT syndrome, organic heart disease, electrolyte abnormalities, cardiotoxic drugs, or adrenergic stimulation. A review of the literature reveals that PVT with normal QT interval and without underlying cause is quite rare. We report a case of idiopathic spontaneous PVT with structurally normal heart and without electrolyte abnormalities, drug reactions, or evidence of catecholamine induced arrhythmia. We also review the literature on the electrocardiographic characteristics and management of idiopathic PVT.
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