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Isolation and Characterization of Dendritic Cells and Macrophages from the Mouse Intestine
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Vasoactive intestinal peptide: the dendritic cell --> regulatory T cell axis

Mario Delgado1, Elena Gonzalez-Rey, Doina Ganea

  • 1Department of Biological Sciences, Rutgers University, Newark, NJ, USA.

Annals of the New York Academy of Sciences
|August 5, 2006
PubMed
Summary

Vasoactive intestinal peptide (VIP) and pituitary adenylate cyclase-activating polypeptide (PACAP) promote tolerogenic dendritic cells (tDCs). These tDCs induce regulatory T cells (Treg), establishing antigen-specific tolerance and suppressing immune responses.

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