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Updated: Aug 6, 2026

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Sexual Transmission of American Trypanosomes from Males and Females to Naive Mates
Published on: January 27, 2019
Sexually transmitted diseases treatment guidelines, 2006
1, Kimberly A Workowski, Stuart M Berman
1Division of STD Prevention, National Center for HIV, Viral Hepatitis, STDs, and Tuberculosis Prevention, Atlanta, GA 30333, USA. kgw2@cdc.gov
Summary
Updated guidelines offer new treatment strategies for sexually transmitted diseases (STDs), including expanded diagnostics and antimicrobial recommendations for infections like trichomoniasis and chlamydial infections.
Area of Science:
- Public Health
- Infectious Diseases
- Clinical Medicine
Background:
- The Centers for Disease Control and Prevention (CDC) periodically updates guidelines for sexually transmitted diseases (STDs) treatment.
- The 2002 Sexually Transmitted Diseases Treatment Guidelines required revision to incorporate new research and emerging challenges.
Purpose of the Study:
- To provide updated, evidence-based recommendations for the diagnosis and treatment of STDs.
- To address emerging issues such as antimicrobial resistance and new diagnostic criteria.
Main Methods:
- Development of guidelines through consultation with STD experts.
- Review and synthesis of current scientific literature and clinical data.
- Incorporation of expert opinion and consensus.
Main Results:
- Expanded diagnostic evaluation for cervicitis and trichomoniasis.
- New antimicrobial recommendations for trichomoniasis.
- Updated information on azithromycin efficacy for chlamydial infections in pregnancy.
- Discussion on Mycoplasma genitalium and trichomoniasis in urethritis/cervicitis.
- Emergence of lymphogranuloma venereum (LGV) proctitis in men who have sex with men (MSM).
- Revised criteria for neurosyphilis diagnosis.
- Emergence of azithromycin-resistant Treponema pallidum.
- Increasing prevalence of quinolone-resistant Neisseria gonorrhoeae in MSM.
- Revised discussion on hepatitis C sexual transmission.
- Guidelines for postexposure prophylaxis after sexual assault.
- Expanded STD prevention strategies.
Conclusions:
- The updated guidelines reflect advancements in STD diagnosis, treatment, and prevention.
- Addressing antimicrobial resistance and emerging pathogens is crucial for effective STD management.
- Comprehensive prevention strategies remain essential for controlling STD transmission.
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