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Updated: Aug 6, 2026

Discovery and Synthesis Optimization of Isoreticular Al(III) Phosphonate-Based Metal-Organic Framework Compounds Using High-Throughput Methods
Published on: October 6, 2023
Synthesis and properties of cordycepin intercalates of Mg-Al-nitrate layered double hydroxides
Qin Zheng Yang1, Jing Yang, Chang Kai Zhang
1School of Food and Bioengineering, Shandong Institute of Light Industry, Jinan 250100, PR China. yangqinzheng@sina.com
Abstract:
Layered double hydroxides (LDHs) were investigated as cordycepin delivery nanocarriers for the first time in this study. Negatively charged biomolecule-cordycepin was intercalated in the gallery spaces of [Mg-Al-NO(3)] as the charge-compensating species, which was confirmed by the results of XRD, FT-IR, TEM, CZE and electrophoretic mobility. Cell experiment suggested that the new bio-LDH nanohybrid could prevent cordycepin decomposition by adenosine deaminase. This new formulation could possibly be used as a novel form cordycepin intravenous injection.
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