Antibacterial properties of the bicyclic pyrazolidinones
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N E Allen1, J N Hobbs, D A Preston
1Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana 46285.
The Journal of Antibiotics
|January 11, 1990
Abstract:
LY173013 and LY186826 are bicyclic pyrazolidinones containing a novel aza-gamma-lactam ring structure. The antibacterial properties of these compounds appear to be related to those of beta-lactam antibiotics in that both classes of compounds share certain common binding molecules such as beta-lactamases and penicillin-binding proteins.