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Published on: July 12, 2011
Pseudomelanosis of the bladder: a case report
Roos E Wieringa1, Hans J Blaauwgeers, George van Andel
1Department of Urology, Onze Lieve Vrouwe Gasthuis, Amsterdam, The Netherlands.
Acta Cytologica
|August 12, 2006
Summary
Pseudomelanosis vesica, a rare urinary tract pigmentation, is described. This benign condition involves melanin-like pigment deposits in the bladder urothelium without atypical cells.
Area of Science:
- Urology
- Pathology
- Gastroenterology
Background:
- Pseudomelanosis is pigment deposition, commonly seen in the colon (pseudomelanosis coli).
- Pigmentation of the urothelium, termed melanosis vesica, involves melanin deposition without atypia.
- True melanosis of the bladder is an uncommon condition.
Observation:
- A 52-year-old male presented with macroscopic hematuria.
- Cystoscopy and microscopic examination revealed urothelial pigmentation.
- The condition was diagnosed as pseudomelanosis vesica.
Findings:
- The bladder urothelium showed deposits of melanin-like pigment.
- No detectable melanocytes were present.
- The pigment was also detectable by urine cytology.
Implications:
- Pseudomelanosis vesica represents a newly described benign lesion in the urinary tract.
- This finding expands the understanding of pigmentary conditions affecting the urinary system.
- Further research may clarify the etiology and clinical significance of pseudomelanosis vesica.
