Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

The Comparative Toxicogenomics Database (CTD): a resource for comparative toxicological studies.

C J Mattingly1, M C Rosenstein, G T Colby

  • 1Mount Desert Island Biological Laboratory, Department of Bioinformatics, Salisbury Cove, Maine 04672, USA. cmattin@mdibl.org

Journal of Experimental Zoology. Part A, Comparative Experimental Biology
|August 12, 2006
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A need to know.

The Physician and sportsmedicine·2016
Same author

A need to know.

The Physician and sportsmedicine·2016
Same author

Cardiovascular Aspects of Aging (Part 1 of 2).

The Physician and sportsmedicine·2016
Same author

Exercise Guidelines for the Elderly (Part 2 of 2).

The Physician and sportsmedicine·2016
Same author

A need to know.

The Physician and sportsmedicine·2016
Same author

a need to know.

The Physician and sportsmedicine·2016
Same journal

The outermost layer of egg-jelly is crucial to successful fertilization in the newt, Cynops pyrrhogaster.

Journal of experimental zoology. Part A, Comparative experimental biology·2006
Same journal

Nitrogen metabolism and excretion in the aquatic chinese soft-shelled turtle, Pelodiscus sinensis, exposed to a progressive increase in ambient salinity.

Journal of experimental zoology. Part A, Comparative experimental biology·2006
Same journal

Caudal autotomy and regeneration in lizards.

Journal of experimental zoology. Part A, Comparative experimental biology·2006
Same journal

Ultrastructure of the male genital ducts of the clearnose skate Raja eglanteria.

Journal of experimental zoology. Part A, Comparative experimental biology·2006
Same journal

Regulation of immunocompetence by different androgen metabolites in a blenny with alternative reproductive tactics.

Journal of experimental zoology. Part A, Comparative experimental biology·2006
Same journal

Uterine motility in the reptile Anolis carolinensis: interactive effects of tension, prostaglandins, calcium, and vasotocin.

Journal of experimental zoology. Part A, Comparative experimental biology·2006
See all related articles

The Comparative Toxicogenomics Database (CTD) links environmental chemicals to gene interactions, aiding human health research. It enables cross-species studies to understand chemical impacts and genetic susceptibility.

Area of Science:

  • Environmental health sciences
  • Genomics
  • Toxicology

Background:

  • Chronic diseases arise from complex interactions between environmental factors and genes.
  • Understanding these interactions is crucial for public health.
  • Environmental chemicals can significantly impact human health through biological pathways.

Purpose of the Study:

  • To develop and promote the use of the Comparative Toxicogenomics Database (CTD).
  • To identify and understand interactions between environmental chemicals and genes.
  • To facilitate cross-species comparative studies for toxicogenomics research.

Main Methods:

  • Developing a publicly available database (CTD).
  • Identifying chemical-gene interactions.

Related Experiment Videos

  • Utilizing cross-species comparative sequence studies and diverse animal models.

    • Main Results:

    • CTD provides a resource for exploring chemical-gene interactions.
    • The database supports comparative toxicogenomics research.
    • Facilitates understanding of molecular mechanisms of environmental chemical action.

    Conclusions:

    • The Comparative Toxicogenomics Database (CTD) is a valuable resource for environmental health research.
    • Cross-species comparative approaches are essential for understanding toxicological mechanisms.
    • CTD aids in elucidating the genetic basis of differential susceptibility to environmental chemicals.