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Five-year outcomes after stenting of unprotected left main coronary artery stenosis in patients with normal left

Bong-Ki Lee1, Myeong-Ki Hong, Cheol Whan Lee

  • 1Department of Internal Medicine, Kangwon National University Hospital, Kangwon National University College of Medicine, Chunchon, Kangwon-do, Korea.

International Journal of Cardiology
|August 15, 2006
PubMed

Insights

Stenting unprotected left main coronary artery (LMCA) stenosis in patients with normal left ventricular function shows sustained favorable outcomes up to 5 years. This interventional cardiology approach demonstrates long-term efficacy in managing complex coronary artery disease.

Area of Science:

  • Cardiology
  • Interventional Cardiology
  • Vascular Surgery

Background:

  • Unprotected left main coronary artery (LMCA) stenosis poses significant risks.
  • Stenting is a common intervention for coronary artery disease.
  • Long-term outcomes of LMCA stenting require continued evaluation.

Purpose of the Study:

  • To assess the 5-year clinical outcomes of patients undergoing stenting for unprotected LMCA stenosis.
  • To evaluate the safety and efficacy of stenting in this high-risk patient group.

Main Methods:

  • A cohort of 187 patients with unprotected LMCA stenosis and normal left ventricular function underwent elective stenting.
  • Patients were followed for major adverse cardiac events (MACE), including death, myocardial infarction (MI), and target lesion revascularization (TLR).
  • Follow-up included clinical examinations and interviews, with angiography at 6 months.

Main Results:

  • Procedural success rate was 99.5% with low in-hospital complications.
  • Six-month angiographic restenosis rate was 33.3%.
  • At 5 years, freedom from MACE was 77.5%. TLR was required in 20.9% of patients.

Conclusions:

  • Stenting of unprotected LMCA stenosis in patients with preserved left ventricular function yields sustained favorable outcomes up to 5 years.
  • The initial benefits observed post-procedure are maintained long-term.
  • This supports stenting as a viable treatment option for selected patients with unprotected LMCA stenosis.
Abstract

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