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Updated: Jul 28, 2026

A Model for Epilepsy of Infectious Etiology using Theiler's Murine Encephalomyelitis Virus
Published on: June 23, 2022
Multiple reversible MR signal changes caused by Epstein-Barr virus encephalitis
G Hagemann1, H-J Mentzel, H Weisser
1Department of Neurology, Friedrich-Schiller-University, Erlanger Allee 101, 07740 Jena, Germany. hagemann@med.uni-jena.de
Abstract:
This report presents the imaging findings of an unusual case of Epstein-Barr virus (EBV) encephalitis. A young man presented with a short-lasting history of febrile infection, neuropsychologic deficits, ataxia, and seizures. MR imaging revealed fully reversible signal intensities (T2, diffusion-weighted imaging with a decreased apparent diffusion coefficient) in the splenium of the corpus callosum and both posterior hemispheres. EBV infection must be added to the list of differential diagnoses of (reversible) splenial lesions.
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