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Chronic inflammatory demyelinating polyneuropathy associated with idiopathic hemochromatosis
Sonoko Misawa1, Satoshi Kuwabara, Shinji Matsuda
1Department of Neurology, Chiba University School of Medicine, Chiba.
Abstract:
We describe a 50-year-old woman who developed chronic inflammatory demyelinating polyneuropathy (CIDP) one year after onset of hemochromatosis. Electrodiagnostic studies showed evidence of multifocal demyelination. Marked hypergammaglobulinemia with positive anti-nuclear and anti-DNA antibodies was found. Corticosteroid treatment resulted in a significant lessening of neurological symptoms. This is the first case of CIDP with hemochromatosis. The association may be coincidental, but the altered immune system by hemochromatosis was possibly related to the development of CIDP in this patient.
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