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[Angiomatous meningioma and epilepsy in a 2.6-years-old girl]

R Sangermani1, C Arienta, M Tonella

  • 1U.O. Pediatria e Patologia Neonatale H.S. Carlo Borromeo Milano.

La Pediatria Medica E Chirurgica : Medical and Surgical Pediatrics
|August 17, 2006
PubMed

Insights

Meningo-angiomatosis (MA) is a rare brain lesion causing refractory seizures in a young girl. Surgical removal of the left temporal lobe lesion confirmed the diagnosis of MA.

Area of Science:

  • Neurology
  • Neurosurgery
  • Pediatric Neurology

Background:

  • Meningo-angiomatosis (MA) is a rare, benign vascular malformation of the central nervous system.
  • It typically presents in children and young adults with neurological symptoms such as seizures.
  • Refractory epilepsy is a common clinical manifestation, posing significant management challenges.

Observation:

  • A 2.6-year-old girl presented with refractory focal and secondary generalized seizures, beginning at age 2.
  • Magnetic Resonance Imaging (MRI) identified a lesion in the left temporal lobe.
  • The patient underwent surgical resection of the identified lesion.

Findings:

  • Histopathological examination of the resected lesion confirmed the diagnosis of meningo-angiomatosis (MA).
  • The lesion exhibited characteristic features of MA, including proliferation of meningothelial and vascular elements.

Implications:

  • This case highlights MA as a potential cause of refractory epilepsy in pediatric patients.
  • Early diagnosis and surgical intervention may be crucial for seizure control in MA.
  • Further research into the pathogenesis and optimal management of MA is warranted.

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