Related Experiment Video
Updated: Aug 6, 2026

Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates
Published on: September 5, 2017
[Geospatial analysis of tuberculosis in Tokyo]
Hirotoshi Watase1, Yoshiko Nakanishi
1Fukagawa Health Consultation Bureau, 3-4-301, Shirakawa, Koto-ku, Tokyo 135-0021, Japan. h-watase05@city.koto.tokyo.jp
Purpose:
To assess geographic variations in the incidence of tuberculosis in Tokyo.
Methods:
Using information on tuberculosis incidence, 2000 to 2002, from the annual notification report, patients were categorized into 8 groups by sex and age. We then calculated the Standardized Incidence Ratio (SIR) for each of the 23 wards in Tokyo. The SIR map was described by spatial interpolation and evaluated by cross validation. Spatial scan statistics were used to detect the significance of high-risk areas across the region. We compare this with the proportional distribution of those receiving public assistance and according to the SIR.
Results:
The geographic variations of SIR did not show a uniform pattern for each group. Spatial scan statistics clearly identified locations, that were significantly high for male groups over 20 years old. Groups under 20 years old and all female groups did not produce high incidence cluster, which are likely to demonstrate spatial features of the proportion of those receiving public assistance.
Conclusions:
The geographic distribution of the proportion of those receiving public assistance should impact upon the geographic distribution of the high incidence clusters. However, considering the results of the young age group and each female group, we suggest that recent infection risk among local habitants was almost uniform, with a slightly higher tendency in urban locations of Tokyo.
Related Concept Videos
Pulmonary Tuberculosis IV
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
Pulmonary Tuberculosis V
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the progression...
Tuberculosis
Pulmonary Tuberculosis I
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Pulmonary Tuberculosis III
The first classification is based on the development of the disease, and it includes the following categories:
Pulmonary Tuberculosis II
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...