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Related Experiment Videos

Cancer in Jewish migrants to Israel.

D M Parkin1, R Steinitz, M Khlat

  • 1International Agency for Research on Cancer, Lyon, France.

International Journal of Cancer
|April 15, 1990
PubMed
Summary
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Cancer incidence in Israeli Jews varied significantly by birthplace, highlighting potential environmental factors influencing disease risk, especially for esophageal cancer in females. This study explores how migration and residence duration impact these variations.

Area of Science:

  • Epidemiology
  • Oncology
  • Environmental Health

Background:

  • Cancer incidence data from Israel's Jewish population (1961-1981) are analyzed.
  • Wide variations in cancer risk observed based on geographic origin.

Purpose of the Study:

  • To investigate cancer risk variations in relation to birthplace, calendar time, and duration of residence in Israel.
  • To explore the role of environmental agents in cancer etiology among migrant populations.

Main Methods:

  • Analysis of cancer incidence data for 15 cancer types.
  • Comparison of disease risk across different birthplaces and lengths of residence.

Main Results:

  • Significant incidence variations by birthplace observed, ranging from 2-fold for pancreatic cancer to 40-fold for female esophageal cancer.

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  • Risk changes related to duration of residence suggest environmental influences.

    • Conclusions:

    • Birthplace is a critical factor in cancer risk among Israeli Jews.
    • Environmental exposures likely play a significant role in cancer etiology, particularly for migrant groups.
    • Further research is needed to understand the underlying causes of these observed variations.