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Updated: Aug 6, 2026

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Published on: August 9, 2024
Recurrent nodular scleritis preceding an adult TINU syndrome
Ebenezer Daniel1, Sapna Gangaputra, John H Kempen
1Division of Ocular Immunology, The Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA. edaniel4@jhmi.edu
Purpose:
To describe the occurrence of nodular scleritis in a patient developing tubulointerstitial nephritis and uveitis (TINU) syndrome.
Design:
Observational case report.
Method:
The case notes of a 57-year-old female presenting with recurrent nodular scleritis, who later developed interstitial nephritis with bilateral uveitis, were reviewed.
Results:
Common and established causes of scleritis were not present in an adult who developed the TINU syndrome a decade later.
Conclusions:
Although scleritis has not been reported as a tubulointerstitial nephritis-associated ocular inflammation, it may be part of the possible spectrum of ocular inflammation occurring as part of the TINU syndrome.