Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Retrobulbar haemodynamics and morphometric optic disc analysis in primary open-angle glaucoma.

N Plange1, M Kaup, A Weber

  • 1Department of Ophthalmology, RWTH Aachen University, Aachen, Germany. nplange@ukaachen.de

The British Journal of Ophthalmology
|August 18, 2006
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Long-term results after trabeculectomy with 5-fluorouracil].

Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·2013
Same author

[Intraoperative inhibition of fibrosis in modern trabeculectomy].

Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·2013
Same author

[Specifity of optic disc evaluation in healthy subjects with large optic discs and physiologic cupping using confocal scanning laser ophthalmoscopy].

Klinische Monatsblatter fur Augenheilkunde·2013
Same author

[Color Doppler sonography of retrobulbar vessels and hypercapnia in normal tension glaucoma].

Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·2012
Same author

[Quantification of fluorescein angiography in patients with non-arteritic anterior ischemic optic neuropathy].

Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·2011
Same author

[Sensitivity of imaging the peripheral nerve fibre layer using a confocal scanning laser ophthalmoscope to detect glaucoma].

Klinische Monatsblatter fur Augenheilkunde·2010

Blood flow in the central retinal artery and vein is linked to neuroretinal rim damage in primary open-angle glaucoma (POAG). This finding highlights the connection between haemodynamics and glaucoma progression.

Area of Science:

  • Ophthalmology
  • Glaucoma Research
  • Ocular Blood Flow

Background:

  • Previous research indicates reduced retrobulbar haemodynamics in primary open-angle glaucoma (POAG).
  • Understanding haemodynamic influences is crucial for glaucoma management.

Purpose of the Study:

  • To explore the relationship between retrobulbar haemodynamics and neuroretinal rim parameters in POAG patients.
  • To assess if blood flow metrics correlate with structural optic nerve damage.

Main Methods:

  • Fifty-one POAG patients underwent colour Doppler imaging for haemodynamic assessment (ophthalmic artery, central retinal artery (CRA), posterior ciliary arteries (PCA), central retinal vein).
  • Optic disc morphometry was performed using scanning laser tomography, analyzing neuroretinal rim (rim area, rim volume) and retinal nerve fibre layer (RNFL) cross-sectional area.

Related Experiment Videos

Main Results:

  • Peak systolic velocity (PSV) in the CRA showed significant correlation with rim area (r=0.50) and rim volume (r=0.51).
  • Minimum velocities of the central retinal vein correlated significantly with rim volume (r=0.56) and RNFL cross-sectional area (r=0.49).
  • No significant correlations were observed for ophthalmic artery or PCA flow velocities.

Conclusions:

  • Retrobulbar haemodynamics of the central retinal artery and vein are demonstrably correlated with neuroretinal rim damage in POAG.
  • These findings suggest haemodynamic parameters of the CRA and central retinal vein are important indicators of structural damage in POAG.