Cutaneous poisoning syndromes in children: a review

Cindy Jao-Tan1, Elena Pope

  • 1The Hospital for Sick Children, Toronto, Canada.

Insights

Pediatricians must recognize and manage skin poisoning syndromes, including carotenoderma, mercury, dioxin, and arsenic. Early diagnosis and prevention education are crucial for child safety.

Area of Science:

  • Pediatric Toxicology
  • Dermatology
  • Environmental Health

Background:

  • Cutaneous manifestations of poisoning are often overlooked in pediatric care.
  • Emerging environmental toxins pose risks to children's health.

Purpose of the Study:

  • To review pediatric cutaneous poisoning syndromes.
  • To outline diagnostic and therapeutic challenges.
  • To emphasize prevention strategies.

Main Methods:

  • Literature review focusing on pediatric poisoning cases with skin symptoms.
  • Analysis of clinical presentations, diagnostic criteria, and treatment protocols.
  • Inclusion of data from organizations like the American Academy of Pediatrics and CDC.

Main Results:

  • Identified key toxins causing skin conditions: carotenoderma, mercury, dioxin, and arsenic.
  • Highlighted the importance of monitoring low-level element toxicity.
  • Detailed clinical presentations for each poisoning type.

Conclusions:

  • Sporadic cases of pediatric cutaneous poisoning persist despite prevention efforts.
  • Pediatricians require updated knowledge on recognizing and managing these syndromes.
  • Anticipatory guidance and patient education are vital for preventing childhood poisonings.
Abstract

Related Concept Videos

Pharmaceutical Poisoning: Potential Scenarios01:26

Pharmaceutical Poisoning: Potential Scenarios

Pharmaceutical poisoning can occur through various channels, impacting an estimated 2 million hospitalized patients in the U.S. annually with serious adverse drug responses. These scenarios encompass both therapeutic uses, such as drug toxicity, where even standard dosages can lead to severe central nervous system depression, and non-therapeutic exposures, including accidental ingestion by children, and environmental and occupational exposures.Unintentional poisonings often involve exploratory...
Toxidromes: Clinical Features01:30

Toxidromes: Clinical Features

Toxidromes are specific patterns of symptoms resulting from toxic substance exposure. They help in the identification and treatment of poisoning. The symptoms of each toxidrome group indicate poisoning by a certain class of chemicals or drugs.1. Sympathomimetic: Stimulates the sympathetic nervous system. Symptoms include agitation, increased heart rate (HR), blood pressure (BP), respiratory rate (RR), temperature, and pupil size. Drugs like cocaine and amphetamines, along with tremors and...
Prevention of Further Absorption of Poison01:14

Prevention of Further Absorption of Poison

In cases of acute poisoning, the primary objective is to prevent further absorption of the toxic substance into the body. Immediate interventions using various decontamination techniques targeting the gastrointestinal (GI) tract can achieve this. Decontamination is crucial to prevent poison from entering the systemic circulation, which involves washing affected areas with water and mild soap and removing contaminated clothing. Once external decontamination is done, attention must be turned to...
Toxic Reactions: Overview01:26

Toxic Reactions: Overview

When toxic substances penetrate the human body, they disseminate to various tissues, undergoing metabolic changes. This process yields reactive metabolites that may covalently bind with specific target molecules, resulting in toxicity.
Toxicity falls into two primary categories: local and systemic.
Local toxicity appears at the exposure site, such as protein denaturation caused by caustic substances.
In contrast, systemic toxicity requires the toxic agent's absorption and distribution,...
Pharmaceutical Poisoning: Treatment Strategies01:26

Pharmaceutical Poisoning: Treatment Strategies

Treatment strategies for poisoning are a critical aspect of emergency medicine, focusing on preventing the absorption of toxins and enhancing their elimination. When a poisoning incident occurs, the first response is to halt exposure and decontaminate the patient, particularly through gastrointestinal (GI) methods if the poison was ingested.Gastrointestinal Decontamination Techniques:Activated charcoal is the cornerstone of GI decontamination. It works through adsorption, binding the toxin to...
Types of Toxins01:36

Types of Toxins

Humans continually engage with an environment rich in potentially harmful chemicals. These are introduced to our bodies through inhalation, ingestion, or skin contact. These chemicals exist in various forms, such as air and environmental pollutants, agricultural chemicals, organic solvents, and heavy metals.
Air pollutants, primarily gases, pose significant threats to respiratory health, leading to conditions like hypoxia, lung cancer, and in extreme cases, death.
Environmental pollutants like...