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[Procedural learning and anxiolytic effects: electroencephalographic, motor and attentional measures]
Claudio Elidio Portella1, Julio Guilherme Silva, Victor Hugo Bastos
1Laboratório de Mapeamento Cerebral e Integração Sensório-motor, IPUB, Universidade Federal do Rio de Janeiro, Rua Filgueiras Lima 68/104, 20950-050 Rio de Janeiro RJ, Brazil.
Abstract:
The objective of the present study was to evaluate attentional, motor and electroencephalographic (EEG) parameters during a procedural task when subjects have ingested 6 mg of bromazepam. The sample consisted of 26 healthy subjects, male or female, between 19 and 36 years of age. The control (placebo) and experimental (bromazepam 6 mg) groups were submitted to a typewriting task in a randomized, double-blind design. The findings did not show significant differences in attentional and motor measures between groups. Coherence measures (qEEG) were evaluated between scalp regions, in theta, alpha and beta bands. A first analysis revealed a main effect for condition (Anova 2-way--condition versus blocks). A second Anova 2-way (condition versus scalp regions) showed a main effect for both factors. The coherence measure was not a sensitive tool at demonstrating differences between cortical areas as a function of procedural learning.
