Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Inappropriate ICD therapy: does device configuration make a difference.

Dwarakraj Soundarraj1, Ranjan K Thakur, Joseph C Gardiner

  • 1Thoracic and Cardiovascular Institute, Michigan State University, Lansing, Michigan 48910, USA.

Pacing and Clinical Electrophysiology : PACE
|August 23, 2006
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Catheter ablation of epicardial premature ventricular complexes in patients with and without cardiac scar.

Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing·2026
Same author

Associations of endocrine disrupting chemicals with anogenital distance across infancy.

The Journal of clinical endocrinology and metabolism·2026
Same author

Patients Experiencing Unsuccessful Defibrillation From Implantable Cardiac Devices Remain at Elevated Risk Despite Procedural Management.

Journal of cardiovascular electrophysiology·2026
Same author

Multimodality Image Integration of FDG-PET and CMR Into Electroanatomic Mapping Identifies Electrophysiologic Signatures of Myocardial Inflammation in Cardiac Sarcoidosis.

JACC. Cardiovascular imaging·2026
Same author

Bachmann's Bundle-Related Atrial Tachycardias Following Catheter Ablation of Persistent Atrial Fibrillation.

Journal of cardiovascular electrophysiology·2026
Same author

Multicentric reticulohistiocytosis.

Cleveland Clinic journal of medicine·2026

Dual chamber implantable cardioverter defibrillators (ICDs) significantly reduce inappropriate therapy compared to single chamber ICDs, primarily due to better discrimination of supraventricular tachycardias. This finding is crucial for optimizing patient care and device selection.

Area of Science:

  • Cardiology
  • Biomedical Engineering
  • Medical Device Technology

Background:

  • Inappropriate implantable cardioverter defibrillator (ICD) therapy (IT) is a frequent complication.
  • Supraventricular tachycardias (SVT) commonly trigger inappropriate ICD shocks.
  • Dual-chamber ICDs (D-ICDs) may offer improved discrimination of SVT compared to single-chamber ICDs (S-ICDs).

Purpose of the Study:

  • To compare the incidence of inappropriate therapy (IT) between D-ICDs and S-ICDs.
  • To evaluate the long-term event-free survival rates for patients with D-ICDs versus S-ICDs.
  • To identify factors associated with inappropriate ICD therapy.

Main Methods:

  • Retrospective chart review of 386 patients with ICDs implanted for AHA class I indications.

Related Experiment Videos

  • Intracardiac electrograms used to classify shocks as appropriate or inappropriate.
  • Multivariate analysis to assess associations with patient characteristics.

    • Main Results:

    • Patients with D-ICDs had a significantly lower incidence of IT (5.4%) compared to S-ICDs (22.3%).
    • Event-free survival rates at 4 years were higher for D-ICD patients (89%) than S-ICD patients (66.4%).
    • Supraventricular tachycardias were the most common cause of IT.

    Conclusions:

    • D-ICDs are associated with a lower likelihood of receiving inappropriate therapy compared to S-ICDs.
    • Device type (D-ICD vs. S-ICD) is a significant factor in preventing inappropriate shocks.
    • Improved SVT discrimination by D-ICDs contributes to reduced inappropriate therapy.