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Matrix control of stem cell fate.

Sharona Even-Ram1, Vira Artym, Kenneth M Yamada

  • 1Craniofacial Developmental Biology and Regeneration Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD 20892, USA.

Cell
|August 23, 2006
PubMed
Summary

Researchers discovered that the elasticity of the matrix microenvironment controls stem cell differentiation. Changing substrate stiffness directs human mesenchymal stem cells toward neuronal, muscle, or bone lineages.

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