Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Monolithic media in microfluidic devices for proteomics.

Kyung Won Ro1, Ranu Nayak, Daniel R Knapp

  • 1Department of Cell and Molecular Pharmacology and Experimental Therapeutics, Medical University of South Carolina, Charleston, SC 29425, USA.

Electrophoresis
|August 24, 2006
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Bio-inspired stearic acid functionalized polylactic acid nanofibers with nanodome architecture for enhanced oil-water separation.

Environmental science and pollution research international·2026
Same author

Natural wax-assisted anisotropic crystallization on hierarchical polydimethylsiloxane sponge: Harnessing interfacial surface energy for efficient oil-water mixture and nanoemulsion separation.

Journal of colloid and interface science·2025
Same author

Emerging advancements in ecofriendly nanosorbent technology accompanied with natural fillers: a systematic review.

Nanotechnology·2025
Same author

Advances in targeted therapy for inflammatory breast cancer: nanomaterials, conventional treatments, and clinical applications.

Nanotechnology·2025
Same author

Revealing miRNAs' Janus-Faced Nature: Transforming Cold Tumours into Immunotherapy Hotspots and Overcoming Chemoresistance.

MicroRNA (Shariqah, United Arab Emirates)·2025
Same author

Combating chemoresistance: Current approaches & nanocarrier mediated targeted delivery.

Biochimica et biophysica acta. Reviews on cancer·2025
Same journal

Kinship Inferences for Second-Degree Relatives With a Combination of STRs and Microhaplotypes.

Electrophoresis·2026
Same journal

Optimisation of Electrokinetic Extraction System: Colourimetric Determination of Copper (II) in Sand Using Polymer Inclusion Membrane.

Electrophoresis·2026
Same journal

Novel Phloroglucinol Derivatives as Neuraminidase Inhibitors Identified From Humulus lupulus L. Extract by At-Line Nanofractionation Platform.

Electrophoresis·2026
Same journal

Protein-Based High-Performance Liquid Chromatography and Cyclodextrin-Capillary Electrokinetic Chromatography for the Chiral Separation of Azoles.

Electrophoresis·2026
Same journal

Dynamics of Heparin Translocations Through Solid-State Nanopores.

Electrophoresis·2026
Same journal

Production of Protein Hydrolysates and Bioactive Peptides From Lablab purpureus and Macrotyloma uniflorum via Optimized Extraction and Proteolysis Protocols.

Electrophoresis·2026
See all related articles

Integrated microfluidic devices for proteomics benefit from in situ fabrication of monolithic media. UV-initiated photopolymerization allows precise placement of multiple analytical components within microchips.

Area of Science:

  • Analytical Chemistry
  • Materials Science
  • Biotechnology

Background:

  • Integrated microfluidic devices are crucial for efficient proteomic studies.
  • In situ fabrication of monolithic media is a key technique for creating microchip components.
  • This method offers advantages in simplicity, precursor availability, and chemical versatility.

Purpose of the Study:

  • To review preparation methods for monolithic media.
  • To explore the application of monolithic media as microfluidic analytical components.
  • To highlight the role of UV-initiated photopolymerization in microchip fabrication.

Main Methods:

  • Summarizing existing literature on monolithic media preparation.
  • Discussing the use of UV-initiated photopolymerization with photomasks.

Related Experiment Videos

  • Analyzing the integration of various analytical components (columns, reactors, extractors, valves) into microchips.

    • Main Results:

    • In situ fabrication of monolithic media is a rapidly developing area.
    • UV-initiated photopolymerization enables precise patterning of multiple components on a single microchip.
    • Monolithic media offer a simple and versatile approach for creating microfluidic analytical devices.

    Conclusions:

    • Monolithic media fabrication is a promising strategy for advanced microfluidic devices.
    • UV-initiated photopolymerization is a powerful tool for creating complex microchip architectures.
    • This approach facilitates the development of integrated systems for high-throughput proteomics.