[Problems with infection in surgical hospital. Meeting with XXI century]

Uncontrollable application of antibiotics (AB), changing nature of microorganisms, insufficient intrahospital epidemiological control causes significant difficulties in the treatment of severe intrahospital infections. Strategy for the therapy quality improvement includes elaboration of the AB application formularies in every division, the nosocomial infections treatment protocols, restriction of certain AB application by special indications, the AB administration change in 48-72 h of its application in accordance to indications, and, if possible, change of the wide specter AB by preparations of more specific action, education of medical personnel on following prophylaxis regimen for hospital infections.