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Updated: Jul 20, 2026

Comparative Proteomic Analysis of Whole Kidney, Medulla, and Cortical Tubules in Diabetic Pathogenesis of Kidney Injury in Mice
Published on: May 2, 2025
Functional and structural renal changes in the early stages of obesity
Vashu Thakur1, Stephen Morse, Efrain Reisin
1Section of Nephrology, Department of Medicine, Louisiana State University School of Medicine, New Orleans, La., USA.
Abstract:
Obesity is an epidemic of colossal proportion, and the healthcare system has been singularly unable to abate this growing threat to society. Two-thirds of US adults are now overweight or obese. Also, the incidence of obesity is increasing in children and adolescents at an alarming rate. The mechanisms of kidney damage, can be both direct and consequential from hypertension and diabetes mellitus. Both hemodynamic and hormonal effects of obesity are discussed. Benefits of weight loss and pharmacological treatment are evaluated.
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