Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Recurrent symptoms after ventricular pacing in unexplained syncope.

A P Fitzpatrick1, C M Travill, P E Vardas

  • 1Cardiac Department, Westminster Hospital, London, England.

Pacing and Clinical Electrophysiology : PACE
|May 1, 1990
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Has denigration of career choice within medicine improved in the UK over the last decade?

Education for primary care : an official publication of the Association of Course Organisers, National Association of GP Tutors, World Organisation of Family Doctors·2026
Same author

Search for a Hidden Sector Scalar from Kaon Decay in the Dimuon Final State at ICARUS.

Physical review letters·2025
Same author

Optimizing diagnostic strategies for sudden arrhythmic death syndrome families; time to focus on age and sex differences?

European journal of preventive cardiology·2025
Same author

School-based indicated prevention interventions for anxiety in children and adolescents: A commentary on a systematic review.

British journal of child health·2024
Same author

Quasi-periodic X-ray eruptions years after a nearby tidal disruption event.

Nature·2024
Same author

Using AI/ML to predict blending performance and process sensitivity for Continuous Direct Compression (CDC).

International journal of pharmaceutics·2024
Same journal

Dual Coronary Sinus Lead Strategy to Avoid Tricuspid Valve Traversal in Biventricular Pacing.

Pacing and clinical electrophysiology : PACE·2026
Same journal

A Case of Permanent Pacemaker Implantation via the Epicardial Approach Using the 3830 Lead in an 11-Day-Old Neonate (With Follow-Up of the Above Case).

Pacing and clinical electrophysiology : PACE·2026
Same journal

Cryoballoon Versus Radiofrequency Ablation for Persistent Atrial Fibrillation: Meta-Analysis of Randomized Trials.

Pacing and clinical electrophysiology : PACE·2026
Same journal

Tilt Test Duration in Suspected Vasovagal Syncope: Temporal Patterns and Diagnostic Yield in Patients From Central China.

Pacing and clinical electrophysiology : PACE·2026
Same journal

Combined Leadless Pacing and Subcutaneous ICD Therapy in Long QT Syndromes.

Pacing and clinical electrophysiology : PACE·2026
Same journal

Association of Anesthesia Modality With Procedural Parameters and Clinical Outcomes in PVI for Atrial Fibrillation.

Pacing and clinical electrophysiology : PACE·2026
See all related articles

Permanent ventricular pacing (VVI) can worsen syncope in some patients by triggering a vasovagal response with retrograde atrioventricular conduction. Further investigation, including tilt testing, is crucial for accurate diagnosis and effective treatment of recurrent syncope.

Area of Science:

  • Cardiology
  • Electrophysiology

Background:

  • Recurrent syncope is a challenging clinical problem.
  • Permanent ventricular pacing (VVI) is sometimes used for unexplained syncope.

Observation:

  • Two patients with unexplained syncope experienced recurrent symptoms after VVI pacemaker implantation.
  • Head-up tilt testing revealed a vasovagal response with bradycardia, complicated by ventricular pacing and retrograde atrioventricular conduction (RAVC), leading to hemodynamic deterioration and syncope recurrence.

Findings:

  • Electrophysiological studies excluded other causes of syncope and confirmed RAVC.
  • Upgrading to dual-chamber pacing (DDI) improved one patient, while the other continued to have symptoms due to the vasodepressor component.
  • Cardiac pacing alone is ineffective for this specific vasovagal syncope phenomenon.

Related Experiment Videos

Implications:

  • Ventricular pacing may exacerbate syncope in susceptible individuals.
  • Comprehensive diagnostic evaluation, including tilt testing, is essential for appropriate syncope management.
  • No definitive therapy currently exists for this complex vasovagal syncope presentation.