Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Exercise prescription and thrombogenesis.

Jong-Shyan Wang1

  • 1Graduate Institute of Rehabilitation Science and Center for Gerontological Research, Chang Gung University, 259 Wen-Hwa 1st Road, Kwei-Shan, Tao-Yuan, 333, Taiwan. s5492@mail.cgu.edu.tw

Journal of Biomedical Science
|August 26, 2006
PubMed
Summary

Regular moderate exercise offers cardiovascular benefits by reducing blood clot risk. Strenuous exercise, however, can increase this risk, highlighting the importance of exercise intensity for vascular health.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Effect of a Stretching Exercise Program on Work-Related Musculoskeletal Disorders in Operating Room Nurses: A Quasi-Experimental Study.

Workplace health & safety·2026
Same author

Pre-hemodialysis exercise training improves systemic aerobic capacity and platelet bioenergetic efficiency in patients with end-stage renal disease.

Life sciences·2026
Same author

Hyperosmotic stress-induced impairment of erythrocyte deformability correlates with reduced aerobic capacity in end-stage renal disease.

Microvascular research·2026
Same author

Intelligent circuit exercise training improves platelet mitochondrial bioenergetic efficiency in sedentary men.

European journal of applied physiology·2025
Same author

Eccentric cycling for chronic respiratory disease: Does helmet ventilation add value? A randomized controlled trial.

Chronic respiratory disease·2025
Same author

Acute effects of ischemic preconditioning and isometric exercise on blood pressure in prehypertensive males.

Journal of exercise science and fitness·2025

Area of Science:

  • Exercise physiology
  • Cardiovascular health
  • Thrombosis research

Background:

  • Lifestyle habits like exercise significantly impact vascular thrombotic events.
  • Vigorous exercise can transiently increase cardiac arrest risk, while regular moderate exercise reduces cardiovascular disease (CVD) risk.
  • Mechanisms behind these paradoxical effects on thrombosis require elucidation.

Purpose of the Study:

  • To review the effects of acute exercise, endurance training, and deconditioning on thrombosis.
  • To analyze the underlying mechanisms influencing platelets, coagulation, and fibrinolysis.
  • To determine optimal exercise strategies for preventing thrombotic events and CVD progression.

Main Methods:

  • Literature review of studies on acute exercise, endurance training, and deconditioning.

Related Experiment Videos

  • Analysis of research on exercise effects on platelet reactivity, coagulation, and fibrinolysis.
  • Categorization of acute exercise intensity based on VO(2 max) percentages.

    • Main Results:

    • Light exercise (< or = 49% VO(2 max)) has no effect on platelets/coagulation but increases fibrinolysis.
    • Moderate exercise (50-74% VO(2 max)) suppresses platelet reactivity, enhances fibrinolysis, with unchanged coagulation.
    • Strenuous exercise (> or = 75% VO(2 max)) enhances platelet reactivity, coagulation, and fibrinolysis.
    • Moderate-intensity exercise training reduces resting platelet reactivity and enhances fibrinolysis, with benefits diminishing upon deconditioning.

    Conclusions:

    • Moderate exercise is a safe and effective dosage for inducing anti-thrombotic changes and minimizing CVD risk.
    • Exercise training confers resting anti-thrombotic benefits and modulates responses during strenuous exercise.
    • Favorable anti-thrombotic adaptations from training are reversible with deconditioning, necessitating consistent exercise adherence.