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Pediatric Burkitt's lymphoma: CT findings
Atheel A Kamona1, Maan A El-Khatib, Maisa Y Swaidan
1Diagnostic Radiology, King Hussein Cancer Center, Amman, Jordan.
Abdominal Imaging
|August 26, 2006
Summary
Computed tomography (CT) is crucial for diagnosing pediatric Burkitt's lymphoma (BL), revealing common gastrointestinal and nodal involvement. This imaging modality aids in understanding disease distribution and complications in children.
Area of Science:
- Pediatric Oncology
- Radiology
- Medical Imaging
Background:
- Burkitt's lymphoma (BL) is an aggressive non-Hodgkin lymphoma with distinct epidemiological and clinical features.
- Pediatric BL often presents with extranodal involvement, posing diagnostic challenges.
Purpose of the Study:
- To review and analyze computed tomography (CT) scans of pediatric Burkitt's lymphoma (BL) cases.
- To characterize the anatomical distribution and patterns of BL involvement in children.
Main Methods:
- Retrospective analysis of 33 pediatric BL cases diagnosed between 2003 and 2005.
- Review of CT scans to identify sites and extent of disease.
Main Results:
- The gastrointestinal tract was the most common site of involvement (57.5%), followed by kidneys (27.2%) and peritoneum (24.2%).
- Extranodal involvement was observed in the head and neck (24.2%), bone (12.1%), and lungs (9%).
- Abdominal lymphadenopathy was present in 63.6% of patients, with cervical lymphadenopathy in 24.2%.
Conclusions:
- CT is an invaluable tool for characterizing pediatric BL, aiding in diagnosis and staging.
- CT provides critical information on the anatomical distribution, patterns of involvement, and complications of BL in children.