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A New Approach for the Comparative Analysis of Multiprotein Complexes Based on 15N Metabolic Labeling and Quantitative Mass Spectrometry
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Advances in the analysis of dynamic protein complexes by proteomics and data processing.

Peter Schubert1, Michael D Hoffman, Matthew J Sniatynski

  • 1The Biomedical Research Centre, University of British Columbia, 2222 Health Sciences Mall, Vancouver, BC, V6T 1Z3, Canada. kast@brc.ubc.ca

Analytical and Bioanalytical Chemistry
|August 26, 2006
PubMed
Summary

New proteomic and computational tools enhance the study of signal transduction pathways. These advancements improve the analysis of protein complexes and post-translational modifications, offering deeper insights into cellular signaling networks and disease mechanisms.

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