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Related Experiment Videos

Enterococcal infection in children.

Karina M Butler1

  • 1Pediatric Infectious Diseases, Our Lady's Children's Hospital Crumlin & The Children's University Hospital, Dublin, Ireland. Karina.butler@olhsc.ie

Seminars in Pediatric Infectious Diseases
|August 29, 2006
PubMed
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Enterococci are a growing cause of hospital infections due to antibiotic resistance and environmental survival. Continued efforts in infection control and rational antibiotic use are crucial to combat this threat.

Area of Science:

  • Infectious Diseases
  • Microbiology
  • Hospital Epidemiology

Background:

  • Enterococci have emerged as a significant cause of nosocomial infections.
  • Factors contributing to their rise include susceptible hosts, device use, and antibiotic exposure.
  • Enterococci's ability to acquire resistance and survive environmentally facilitates their spread.

Purpose of the Study:

  • To review the emergence of enterococci as nosocomial pathogens.
  • To discuss the challenges posed by antibiotic-resistant strains.
  • To highlight the importance of infection control and antibiotic stewardship.

Main Methods:

  • Literature review and synthesis of current knowledge on enterococcal infections.
  • Analysis of factors contributing to the rise of nosocomial enterococcal infections.

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  • Discussion of therapeutic challenges and strategies for resistance prevention.

    • Main Results:

    • Enterococci are increasingly implicated in nosocomial bacteremia, particularly in intensive care settings.
    • The spread of resistant enterococcal strains presents a significant therapeutic challenge.
    • Newer agents like linezolid offer temporary solutions, but resistance is emerging.

    Conclusions:

    • Continued vigilance and multifaceted strategies are essential to prevent the emergence and spread of antibiotic resistance in enterococci.
    • Rational antibiotic use, robust infection control measures, and education are critical.
    • There is a need for ongoing research and development of new therapeutic options.