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Updated: Jul 20, 2026
Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents
Published on: February 15, 2022
Comparison of visual function after epiretinal membrane removal by 20-gauge and 25-gauge vitrectomy
Kazuaki Kadonosono1, Tadashi Yamakawa, Eiichi Uchio
1Department of Ophthalmology, Yokohama City University Medical Center, Yokohama, Japan. kado@med.yokohama-cu.ac.jp
Purpose:
To compare the efficacy and safety of 25-gauge vitrectomy with 20-gauge vitrectomy for macular pucker.
Design:
Randomized clinical study.
Methods:
Sixty-seven eyes (67 patients) with macular pucker were prospectively and randomly assigned to undergo 20-gauge vitrectomy or 25-gauge vitrectomy as a control group. Main outcome measurements consisted of best-corrected visual acuity (BCVA), mean induced astigmatism, total operation time, and postoperative complications.
Results:
The mean BCVA at baseline and at one month and six months after surgery was 20/78, 20/62, and 20/42, respectively, in the 20-gauge group, and 20/85, 20/45, and 20/40 in the 25-gauge group. A significant difference in change in the logarithm of the minimal angle of resolution of BCVA between 20-gauge and 25-gauge was found at one month (-0.10 vs -0.269, P < .001), but not at six months (-0.327 vs -0.276, P > .01).
Conclusions:
If faster visual improvement is desired, 25-gauge vitrectomy may be preferable to 20-gauge vitrectomy for macular pucker.
