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Updated: Jul 20, 2026

Studying Cell Cycle-regulated Gene Expression by Two Complementary Cell Synchronization Protocols
12:02

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Published on: June 6, 2017

HBx-dependent cell cycle deregulation involves interaction with cyclin E/A-cdk2 complex and destabilization of

Atish Mukherji1, Vaibhao C Janbandhu, Vijay Kumar

  • 1Virology Group, International Centre for Genetic Engineering and Biotechnology, P.O. Box 10504, Aruna Asaf Ali Marg, New Delhi-110067, India.

The Biochemical Journal
|August 31, 2006
PubMed
Summary

The hepatitis B virus X protein (HBx) disrupts cell cycle control, promoting liver cancer. HBx directly interacts with cell cycle regulators, independent of its transactivation role, to drive proliferation.

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