Standards in gene expression microarray experiments
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Updated: Jul 20, 2026
09:27
DNA Microarrays: Sample Quality Control, Array Hybridization and Scanning
Published on: March 15, 2011
1Chemical Science and Technology Laboratory, National Institute of Standards and Technology, Gaithersburg, MD, USA.
Methods in Enzymology
|August 31, 2006
Abstract:
The use of standards in gene expression measurements with DNA microarrays is ubiquitous--they just are not yet the kind of standards that have yielded microarray gene expression profiles that can be readily compared across different studies and different laboratories. They also are not yet enabling microarray measurements of the known, verifiable quality needed so they can be used with confidence in genomic medicine in regulated environments.
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Gene expression is the process in which DNA directs the synthesis of functional products, that is, proteins. Cells can regulate gene expression at various stages. It allows organisms to generate different cell types and enables cells to adapt to internal and external factors.
Genetic Information Flows from DNA to RNA to Protein
A gene is a stretch of DNA that serves as the blueprint for functional RNAs and proteins. Since DNA is made up of nucleotides and proteins consist of amino...