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Precocious expression of NAPA-73, an intermediate filament-associated protein, during nervous system and heart
1Department of Cell Biology and Anatomy, Vollum Institute, Oregon Health Sciences University, Portland 97201.
Annals of the New York Academy of Sciences
|January 1, 1990
Abstract:
A monoclonal antibody was generated, against early neural crest-derived cells, which recognizes an epitope present on a novel intermediate filament-associated protein. This protein has been named NAPA-73 and is expressed by progenitor cells of the nervous system and heart. Biochemical and ultrastructural studies indicate that this protein associates with bundles of intermediate filaments and therefore may play a role in the determination of cell shape.