Related Experiment Video
Updated: Jul 20, 2026

08:39
A Murine Model of Hemodialysis Access-Related Hand Dysfunction
Published on: May 31, 2022
Vascular access for hemodialysis.
Rick Hayashi1, Edmund Huang, Allen R Nissenson
1UCLA Medical Center, Los Angeles, CA, USA.
Nature Clinical Practice. Nephrology
|August 31, 2006
Summary
Adequate vascular access is crucial for dialysis patients. This review examines the 2000 K/DOQI guideline and subsequent updates for optimal dialysis access and complication management in end-stage renal disease.
Area of Science:
- Nephrology
- Vascular Surgery
- Dialysis Medicine
Background:
- Vascular access is critical for dialysis delivery in end-stage renal disease (ESRD).
- Vascular access complications significantly contribute to morbidity and mortality in dialysis patients.
- The 2000 K/DOQI guideline provides a framework for dialysis access management.
Purpose of the Study:
- To review the 2000 K/DOQI clinical practice guideline for dialysis access.
- To incorporate updated information published after the 2000 guideline.
- To provide a comprehensive overview of optimal dialysis access and complication management.
Main Methods:
- Literature review of the 2000 K/DOQI dialysis access guideline.
- Inclusion of subsequent research and updates.
- Synthesis of information on establishment, maintenance, and complication treatment.
Main Results:
- The 2000 K/DOQI guideline offers a foundational framework.
- Subsequent updates address evolving practices and challenges in vascular access.
- Current best practices emphasize proactive management and timely intervention.
Conclusions:
- Optimal vascular access is paramount for effective dialysis.
- Adherence to updated guidelines and continuous learning is essential for minimizing complications.
- This review synthesizes key recommendations for improving patient outcomes in ESRD.
Related Concept Videos
Hemodialysis I: Introduction
Hemodialysis (HD) is a medical treatment that artificially removes waste products, excess fluids, and toxins from the blood when the kidneys are no longer able to perform these functions effectively. In this process, blood is filtered through a semipermeable membrane, allowing for the selective removal of waste while preserving necessary components like blood cells and proteins. Hemodialysis is typically performed in patients with end-stage renal disease (ESRD) or severe kidney...
Hemodialysis II: Procedure and Complications
DialyzersA hemodialysis (HD) dialyzer is a plastic cartridge containing thousands of parallel hollow fibers, which serve as semipermeable membranes. These fibers are typically made from cellulose-based or other synthetic materials. During HD, blood is pumped into the top of the cartridge and distributed among these fibers. Simultaneously, dialysis fluid, known as dialysate, is introduced into the bottom of the cartridge, bathing the outside of the fibers. Across the semipermeable membrane,...
Hemodialysis III: Nursing Management
The nursing management of a patient undergoing hemodialysis includes several critical steps, starting with a thorough assessment before the procedure.Before the Hemodialysis ProcedureFirst, record the patient's vital signs—blood pressure, heart rate, respiratory rate, and temperature—to establish a baseline. This baseline is essential for detecting conditions such as hypotension that could impact the patient's response to dialysis. Document the patient's pre-dialysis weight, as this measurement...
Dialysis
Renal failure occurs when the kidneys lose their ability to filter waste products from the blood effectively. It can be classified into two types: acute renal failure (ARF) and chronic renal failure (CRF).
Acute kidney injury develops suddenly and can be caused by pre-renal causes (e.g., hypovolemia, shock), intrinsic renal causes (e.g., acute tubular necrosis), or post-renal causes (e.g., urinary obstruction). In contrast, chronic renal failure progresses gradually over time and is often...
Acute kidney injury develops suddenly and can be caused by pre-renal causes (e.g., hypovolemia, shock), intrinsic renal causes (e.g., acute tubular necrosis), or post-renal causes (e.g., urinary obstruction). In contrast, chronic renal failure progresses gradually over time and is often...
Dialysis
Dialysis is a diffusion-based purification process that separates analyte molecules from a complex matrix. This is accomplished by allowing molecules in the solution to pass through a semipermeable membrane into a liquid on the other side. The membrane is usually made of cellulose acetate or cellulose nitrate, and the second liquid must be miscible with the solution. Ions (e.g., chloride or sodium) or organic molecules (e.g., glucose) can pass through the membrane pores, which generally have...
Continuous Renal Replacement Therapy
Continuous Renal Replacement Therapy, also known as CRRT, is a procedural treatment for acute kidney injury (AKI) that gradually removes uremic toxins and fluids while maintaining acid-base balance and stabilizing electrolytes. It is particularly useful for hemodynamically unstable patients. Unlike intermittent hemodialysis, which is faster, CRRT provides a gentler approach over 24 hours, closely mimicking the function of natural kidneys. However, CRRT is not ideal for patients with...
