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Asthma: Pathogenesis and Management01:20

Asthma: Pathogenesis and Management

Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
Asthma-I: Introduction01:29

Asthma-I: Introduction

Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
Asthma-II: Pathophysiology and Classification01:26

Asthma-II: Pathophysiology and Classification

Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
Asthma-III: Symptoms and Complications01:24

Asthma-III: Symptoms and Complications

Asthma, a common chronic respiratory condition, is classified considering the frequency and severity of symptoms alongside lung function impairment. Understanding this classification is essential for appropriate treatment and management. Here's a detailed look at the classification of asthma and its clinical features and complications:
Classification of Asthma
Asthma-IV: Diagnostic and Management01:30

Asthma-IV: Diagnostic and Management

The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
Asthma I: Introduction01:28

Asthma I: Introduction

Asthma is a chronic inflammatory disorder of the airways characterized by variable airflow obstruction and heightened bronchial responsiveness to a wide range of triggers. The underlying inflammation leads to airway swelling, mucus hypersecretion, and smooth muscle constriction, all of which narrow the airway lumen and impede airflow. Clinically, asthma presents with recurrent episodes of wheezing, shortness of breath, chest tightness, and coughing, symptoms that typically vary in intensity and...

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Related Experiment Video

Updated: Jun 28, 2026

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
14:39

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma

Published on: November 5, 2010

Asthma and pregnancy.

Mitchell P Dombrowski1

  • 1Department of Obstetrics and Gynecology, St. John Hospital and Wayne State University School of Medicine, Detroit, Michigan 48236, USA. mitchell.dombrowski@stjohn.org

Obstetrics and Gynecology
|September 2, 2006
PubMed
Summary
This summary is machine-generated.

Properly managed asthma in pregnancy leads to good outcomes. Uncontrolled asthma poses risks, but safe medications and monitoring ensure fetal well-being and successful delivery.

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Murine Model of Allergen Induced Asthma
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Methodology for Sputum Induction and Laboratory Processing

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Related Experiment Videos

Last Updated: Jun 28, 2026

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
14:39

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma

Published on: November 5, 2010

Murine Model of Allergen Induced Asthma
08:05

Murine Model of Allergen Induced Asthma

Published on: May 14, 2012

Methodology for Sputum Induction and Laboratory Processing
13:28

Methodology for Sputum Induction and Laboratory Processing

Published on: December 17, 2017

Area of Science:

  • Obstetrics and Gynecology
  • Pulmonology
  • Perinatal Medicine

Background:

  • Asthma affects 4-8% of pregnancies, with outcomes varying based on severity and control.
  • Mild to moderate, well-controlled asthma is linked to positive maternal and infant results.
  • Severe or poorly controlled asthma increases risks for prematurity, cesarean delivery, preeclampsia, and fetal growth restriction.

Purpose of the Study:

  • To outline optimal asthma management strategies during pregnancy.
  • To emphasize the importance of objective lung function monitoring and trigger avoidance.
  • To highlight the safety and efficacy of pharmacologic therapy, particularly inhaled corticosteroids.

Main Methods:

  • Objective monitoring using peak expiratory flow rate (PEFR) and spirometry (forced expiratory volume in 1 second - FEV1).
  • Step-care approach to pharmacologic therapy, prioritizing inhaled corticosteroids for persistent asthma.
  • Aggressive management of asthma exacerbations to maintain maternal oxygenation and fetal well-being.

Main Results:

  • Controlled asthma ensures excellent maternal and perinatal outcomes.
  • Uncontrolled asthma is associated with significant maternal and perinatal complications.
  • Maintaining maternal oxygenation is crucial for fetal health.

Conclusions:

  • Optimal asthma management during pregnancy involves monitoring, trigger control, education, and appropriate medication.
  • Inhaled corticosteroids are safe and effective for persistent asthma in pregnancy.
  • Continued asthma management through labor and breastfeeding is recommended for maternal and infant health.