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Idiopathic hypercalciuria in infants with renal stones

Anita Ammenti1, Erica Neri, Roberta Agistri

  • 1Department of Pediatrics, University of Parma, Parma, Italy.

Pediatric Nephrology (Berlin, Germany)
|September 2, 2006
PubMed

Insights

Idiopathic hypercalciuria (IH) is a common cause of kidney stones and microcalculi in infants. Early screening for IH is recommended in infants presenting with these conditions.

Area of Science:

  • Pediatric Nephrology
  • Urology
  • Metabolic Disorders

Background:

  • Hypercalciuria is a leading cause of renal stones in children over two years old.
  • The prevalence of hypercalciuria in infants is not well-established.
  • Renal stones and microcalculi can occur in infants.

Purpose of the Study:

  • To investigate the prevalence and significance of idiopathic hypercalciuria (IH) in infants with renal stones or microcalculi.
  • To determine if IH is a frequent cause of kidney stones in this age group.

Main Methods:

  • Retrospective case series of infants diagnosed with renal stones or microcalculi between 5 and 19 months of age.
  • Metabolic evaluation of four infants.
  • Diagnosis of idiopathic hypercalciuria (IH) in the evaluated patients.

Main Results:

  • Four infants were diagnosed with renal stones or microcalculi between 5 and 19 months of age.
  • Idiopathic hypercalciuria (IH) was diagnosed in all four evaluated infants.
  • IH was identified as a frequent cause of microcalculi and renal stones in infants.

Conclusions:

  • Idiopathic hypercalciuria (IH) is a significant cause of microcalculi and renal stones in infants.
  • Screening for IH is warranted in infants presenting with renal stones or microcalculi.

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