Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Melt granulation using a twin-screw extruder: a case study.

Barbara Van Melkebeke1, Brenda Vermeulen, Chris Vervaet

  • 1Laboratory of Pharmaceutical Technology, Ghent University, Harelbekestraat 72, B-9000 Ghent, Belgium.

International Journal of Pharmaceutics
|September 5, 2006
PubMed
Summary

Melt granulation using twin-screw extrusion with polyethylene glycols (PEG) binders produced fast-dissolving granules. Optimal granulation temperature and surfactant addition enhanced drug release for immediate-release formulations.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Effect of externally sprayed lubricant combinations on ejection force and physical characteristics of tablets.

International journal of pharmaceutics·2026
Same author

Continuous twin screw wet granulation of low-dose formulations: Impact of process variables and API/binder addition methods on granule quality attributes.

International journal of pharmaceutics·2026
Same author

In-Line Blend Potency Measurements of Low-Dose Formulations Using a Novel Deep-UV LIF Probe in the Feed Frame of a Rotary Tablet Press.

Analytical chemistry·2026
Same author

Correlation between permeability of pectin-ethylcellulose films and drug release from coatings under variable processing conditions.

International journal of pharmaceutics·2026
Same author

Investigating the effects of formulation and manufacturing routes on the tensile strength and disintegration time of tablets containing an HPMC AS-based spray dried powder.

International journal of pharmaceutics·2025
Same author

From print settings to printlet performance: a study on critical quality attributes in pellet-based direct extrusion additive manufacturing.

International journal of pharmaceutics·2025

Failed At:

2026-07-10T15:01:10.334473+00:00

Related Experiment Videos