[Urticaria and mast cells in adolescence]

Area of Science:

• Dermatology
• Allergology
• Pediatrics

Context:

• Adolescents frequently experience physical urticaria (dermographic, cold, solar, cholinergic) triggered by stimuli.
• These conditions, along with mastocytosis, stem from mast cell mediator release.
• Distinct cutaneous symptoms aid in differentiating these from other urticarial subtypes.

Purpose:

• To familiarize readers with physical urticaria and mastocytosis in adolescents.
• To outline the clinical presentations of these conditions.
• To discuss pathogenic factors and therapeutic options.

Summary:

• Physical urticaria and mastocytosis in adolescents are linked to mast cell degranulation.
• Diagnosis is often guided by characteristic skin manifestations.
• Management strategies encompass understanding triggers and available treatments.

Impact:

• Provides a comprehensive overview for clinicians managing adolescent urticarial disorders.
• Highlights the importance of recognizing physical urticaria and mastocytosis.
• Informs therapeutic approaches for improved patient outcomes.