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Updated: Jul 20, 2026

Identification of Virulence Markers of Mycobacterium abscessus for Intracellular Replication in Phagocytes
Published on: September 27, 2018
Microbiology of peritonsillar abscesses
Flavio Akira Sakae1, Rui Imamura, Luiz Ubirajara Sennes
1University Hospital, USP, Brazil. sakaeflavio@yahoo.com.br
Aim:
The objective of the present study was to analyze the microbiology of peritonsillar abscesses.
Methods:
Thirty patients, mean age 24,2 years, with peritonsillar abscesses underwent aspiration of at least 3 mL of pus, which was cultured for aerobes and anaerobes.
Results:
87% samples showed positive cultures. Aerobic or facultative aerobic bacteria were isolated from 23% aspirates, mixed aerobic and anaerobic bacteria from 60%, and anaerobic bacteria from only 3% aspirate. A total of 69 bacterial isolates (34 aerobic and 35 anaerobic) were recovered. The most common aerobic isolate was Streptococcus sp, with Streptococcus pyogenes being identified in 23% of aspirates. The predominant anaerobic isolates were Prevotella sp and Peptostreptococcus sp. Patients had received previous antimicrobial therapy in 63% cases. In this group, 1.8 isolates per specimen were recovered, a lower number than in the untreated group (3.0 per specimen). No significant difference in the species isolated was observed between these two groups.
Conclusion:
Peritonsillar abscess is usually a polymicrobial infection, with predominance of anaerobic bacteria. The number of agents isolated was larger in patients not previously treated with antibiotics, but the use of antimicrobial drugs did not interfere with the type of bacterium isolated.
Insights
Peritonsillar abscesses are typically polymicrobial infections, often involving anaerobic bacteria. Previous antibiotic use reduced the number of bacteria found but did not alter the types of microbes identified.
Area of Science:
- Otolaryngology
- Microbiology
- Infectious Diseases
Background:
- Peritonsillar abscess (PTA) is a common complication of tonsillitis.
- Understanding the microbial etiology of PTA is crucial for effective treatment.
Purpose of the Study:
- To investigate the microbiological characteristics of peritonsillar abscesses.
- To identify the predominant aerobic and anaerobic bacteria involved in PTA.
Main Methods:
- Pus samples from 30 PTA patients were cultured for aerobic and anaerobic bacteria.
- Patients' prior antimicrobial therapy history was recorded.
Main Results:
- 87% of samples yielded positive cultures.
- Mixed aerobic and anaerobic bacteria were most common (60%), followed by aerobes (23%).
- Streptococcus sp. (including Streptococcus pyogenes) was the most frequent aerobic isolate, while Prevotella sp. and Peptostreptococcus sp. predominated anaerobically.
Conclusions:
- Peritonsillar abscess is generally a polymicrobial infection, with a significant presence of anaerobic bacteria.
- While prior antibiotic treatment reduced the number of isolates, it did not change the spectrum of bacteria found in PTA.
Related Concept Videos
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Etiology
Three primary contributing factors have been identified.
Brain Abscess l: Introduction
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Atypical Pneumonia
Acute Pharyngitis
Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice.
Classification
Acute pharyngitis can be categorized based on its underlying cause:
