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Extramammary Paget's disease: isolated localization on the groin--wide local excision with immediate reconstruction
Alexander Dionyssopoulos1, Ioanna Mandekou-Lefaki, Efstratios Vakirlis
1Division of Skin Oncologic Surgery-Plastic Surgery, First Department of Dermatology, Aristotle University of Thessaloniki, Thessaloniki, Greece. alexdion@med.auth.gr
Background:
Extramammary Paget's disease is a rare cutaneous malignancy, which occurring frequently in the elderly and affecting primarily the genital, perianal, and axillary regions. Unfortunately, surgical and ablative treatment modalities for extramammary Paget's disease have a high recurrence rate and are often associated with significant morbidity.
Methods:
We present a case of a 51-year-old Caucasian man with Paget's disease of the right groin. The isolated localization of Paget's disease in the groin is extremely rare. Wide local excision of the tumor is currently the standard of care treatment. All publications found in the literature reporting this rare entity were reviewed for the purpose of further delineating a treatment regimen for this rare pathology.
Results:
Six years after surgery, the patient remains disease free with a very acceptable aesthetic result. Currently, only 11 cases of Paget's disease have been reported with an isolated localization to the groin.
Conclusions:
Paget's disease of the groin has an extremely low incidence. Various treatments are described in the literature, early wide local excision may be the treatment of choice.
