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Vinblastine-induced ultrastructural changes in perisinusoidal cells of the rat liver
Research in Experimental Medicine. Zeitschrift Fur Die Gesamte Experimentelle Medizin Einschliesslich Experimenteller Chirurgie
|September 24, 1975
Abstract:
Vinblastine, given intravenously to rats, leads to disappearance of microtubules, formation of paracrystalline inclusions and accumulation of fat droplets in the cytoplasm of the perisinusoidal cells of the liver suggesting that microtubules of the perisinusoidal cells play a role in lipid metabolism.