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Updated: Jul 20, 2026

Sulfate Separation by Selective Crystallization with a Bis-iminoguanidinium Ligand
Published on: September 8, 2016
A sulfitylation-oxidation protocol for the preparation of sulfates
M Huibers1, Alvaro Manuzi, Floris P J T Rutjes
1Institute for Molecules and Materials, Organic Chemistry, Radboud University Nijmegen, Toernooiveld 1, 6525 ED Nijmegen, The Netherlands.
Abstract:
A novel, high-yielding method for sulfation of alcohols has been developed, proceeding via sulfite- and sulfate diester intermediates. Sulfite diesters serve as versatile sulfate monoester precursors, allowing for transformations that are difficult or impossible with the latter compounds.
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