Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Developing insect models for the study of current and emerging human pathogens.

Lisa R Scully1, Michael J Bidochka

  • 1Department of Biological Sciences, Brock University, ON, Canada.

FEMS Microbiology Letters
|September 9, 2006
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The endophytic fungi Metarhizium, Pochonia, and Trichoderma, improve salt tolerance in hemp (Cannabis sativa L.).

PloS one·2025
Same author

Tripartite interactions of an endophytic entomopathogenic fungus, Asian corn borer, and host maize under elevated carbon dioxide.

Pest management science·2024
Same author

Utilization of <i>Metarhizium</i> as an insect biocontrol agent and a plant bioinoculant with special reference to Brazil.

Frontiers in fungal biology·2024
Same author

The AreA Nitrogen Catabolite Repression Activator Balances Fungal Nutrient Utilization and Virulence in the Insect Fungal Pathogen <i>Beauveria bassiana</i>.

Journal of agricultural and food chemistry·2022
Same author

Three Methods Assessing the Association of the Endophytic Entomopathogenic Fungus <i>Metarhizium robertsii</i> with Non-Grafted Grapevine <i>Vitis vinifera</i>.

Microorganisms·2022
Same author

Profiling Destruxin Synthesis by Specialist and Generalist Metarhizium Insect Pathogens during Coculture with Plants.

Applied and environmental microbiology·2022
Same journal

Genetic basis of R-phase H:z27 antigen expression and phylogenetic relationships of Salmonella enterica serovar Senftenberg.

FEMS microbiology letters·2026
Same journal

Chitin metabolism enhancement by β-N-acetyl-D-glucosaminyl-(1,4)-D-glucosamine in Vibrio is associated with chitin disaccharide transporter.

FEMS microbiology letters·2026
Same journal

The Type III Secretion System plasmid pPHDPT3 of Photobacterium damselae subsp. piscicida is stable in Australian isolates due to conserved non-repetitive genomic architecture.

FEMS microbiology letters·2026
Same journal

Multi-copy aiiA genes encoding quorum-quenching enzymes in Bacillus thuringiensis: identification and functional characterization of the novel AHL-lactonase, AiiA2.

FEMS microbiology letters·2026
Same journal

Recombination mapping identifies a commensal Neisseria subflava origin of mosaic penA 60.001 allele in Neisseria gonorrhoeae.

FEMS microbiology letters·2026
Same journal

Long vs. short read sequencing for microbial ecology of sedimentary environments: a case study from Lake Arnon, Switzerland.

FEMS microbiology letters·2026
See all related articles

Insects offer a valid, ethical, and cost-effective model for studying human diseases, especially opportunistic infections. Their use provides insights into pathogen evolution and host-jumping mechanisms.

Area of Science:

  • Microbiology
  • Pathogenesis
  • Infectious Diseases

Background:

  • Mammalian models are standard for studying human diseases.
  • Insects present a viable alternative for disease research.
  • Opportunistic microorganisms pose a growing health concern.

Purpose of the Study:

  • To validate insects as effective model organisms for studying human diseases.
  • To explore the parallels between insect and mammalian responses to pathogens.
  • To investigate the potential of insects as reservoirs for emerging human pathogens.

Main Methods:

  • Comparative analysis of microbial pathogenesis in insects and mammals.
  • Infection studies using Candida and Pseudomonas spp. in insect models.
  • Evaluation of insect innate immune responses to pathogens.

Related Experiment Videos

Main Results:

  • Insect models demonstrate significant parallels with mammalian systems in microbial pathogenesis.
  • Insect responses to specific pathogen infections correlate well with mouse models.
  • Insects show potential as reservoirs for emerging human pathogens.

Conclusions:

  • Insects serve as a valuable, ethical, and cost-effective alternative to mammalian models for disease research.
  • Insect models facilitate the study of pathogen evolution, virulence factors, and host-jumping.
  • Large-scale insect studies offer rapid screening for opportunistic diseases and insights into emerging pathogens.