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Updated: Jul 20, 2026

Evaluation of the Cognitive Performance of Hypertensive Patients with Silent Cerebrovascular Lesions
Published on: April 23, 2021
Systolic hypertension in elderly patients
1Diagnosis Center, Hôpital Hôtel-Dieu, Paris, France. michel.safar@htd.ap-hop-paris.fr
Abstract:
Pulsatile arterial hemodynamics in cardiovascular diseases indicate that the aortic blood pressure curve may be represented by 2 different phenotypes: one in patients 64 years old and younger and the other in subjects older than 65 years. The 2 blood pressure curves may have exactly the same mean arterial pressure (ie, the same cross-sectional area under the curve) but quite different shapes. In older subjects, systolic blood pressure and pulse pressure are higher, whereas diastolic blood pressure is lower than in younger subjects.
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