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Published on: December 18, 2012
Increased risk for herpetic eye disease in patients with allergic conjunctivitis
Igor Kaiserman1, Nadia Kaiserman, Asher Elhayany
1Department of Ophthalmology, Barzilai Medical Center, Ashkelon, Israel. Igor@Dr-Kaiserman.com
Purpose:
To evaluate the risk of ocular surface herpetic eye disease (osHED) in allergic eye disease.
Methods:
We calculated the risk for osHED in 11,205 patients on antiallergic ocular topical agents compared with 453,069 controls based on filled prescriptions for topical acyclovir between 2001 and 2003.
Results:
Significantly more allergic patients, of all age groups, received treatment for osHED (p < 0.01). The age and gender adjusted relative risk for allergic patients to suffer an osHED event was 2.31 (95% CI: 1.84-2.90), raising to 3.55 (95% CI: 2.0-6.4) in patients that filled > or = 4 antiallergic prescriptions.
Conclusions:
Patients treated for allergic eye disease have an increased risk of osHED.
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