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Pediatric mechanical circulatory support in the United States: past, present, and future
1Department of Pediatric and Congenital Heart Surgery, Children's Hospital, Cleveland Clinic, Cleveland, Ohio 44195, USA.
Insights
Pediatric mechanical circulatory support options are expanding, offering new hope for children with heart failure. Advances in devices like the DeBakey VAD Child and Berlin Heart VAD improve treatment for pediatric heart conditions.
Area of Science:
- Pediatric Cardiology
- Biomedical Engineering
- Cardiovascular Surgery
Background:
- Mechanical circulatory support is standard for adult heart failure.
- Limited options historically existed for pediatric heart failure.
- Extracorporeal membrane oxygenation and centrifugal pumps were primary pediatric modalities.
Purpose of the Study:
- To review recent advances in pediatric mechanical circulatory support.
- To highlight the growing availability of devices for children.
- To discuss promising future innovations in the field.
Main Methods:
- Review of current pediatric mechanical circulatory support devices.
- Analysis of clinical experience with specific VADs (Ventricular Assist Devices).
- Discussion of research and development initiatives.
Main Results:
- Substantial advances in pediatric circulatory support devices have occurred.
- Increased clinical experience with DeBakey VAD Child and Berlin Heart VAD.
- New devices are under development through NHLBI's Pediatric Circulatory Support Program.
Conclusions:
- Pediatric mechanical circulatory support options have significantly improved.
- Current devices offer better solutions for children with heart failure.
- Future innovations promise expanded choices for pediatric mechanical circulatory support.
Abstract:
Mechanical support of the failing myocardium has become standard therapy for adults who fail medical management. Historically, there have been fewer options for children with heart failure. Extracorporeal membrane oxygenation and centrifugal pump-based ventricular assist devices have been the most commonly used circulatory support modalities for pediatrics in the United States. During the last few years, substantial advances in pediatric circulatory support have been made, with greater availability of a number of devices suitable for pediatrics. For example, there has been increasing experience using the DeBakey VAD Child and the Berlin Heart VAD to provide circulatory support for children during this period. A number of innovative devices under development supported by the Pediatric Circulatory Support Program of the National Heart, Lung, and Blood Institute hold great promise for expanded options for pediatric mechanical circulatory support in the future.
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