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Related Experiment Videos

Intracranial chondrosarcoma--case report.

T Miyamori1, H Mizukoshi, K Yamano

  • 1Department of Neurosurgery, Toyama Municipal Hospital.

Neurologia Medico-Chirurgica
|April 1, 1990
PubMed
Summary

A chondroma transformed into a chondrosarcoma in a patient after multiple surgeries. Complete removal and careful follow-up are crucial for managing these intracranial tumors.

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Gliosarcoma of the posterior cranial fossa: MRI findings.

Neuroradiology·1993

Area of Science:

  • Neurosurgery
  • Oncology
  • Pathology

Background:

  • Chondromas are benign cartilaginous tumors.
  • Recurrent or incompletely removed chondromas carry a risk of malignant transformation.
  • Intracranial chondromas can affect cranial nerve function.

Observation:

  • A 54-year-old male presented with symptoms related to cranial nerve involvement.
  • Previous partial removal of intracranial chondromas occurred 6 and 10 years prior.
  • Imaging revealed a large mass in the right middle/posterior fossae and ethmoid sinus.

Findings:

  • Histological examination confirmed a chondrosarcoma with poorly differentiated cartilaginous cells, indicating sarcomatous change.
  • Subtotal tumor removal led to improved function of the second, third, and eighth cranial nerves.

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  • The tumor was extradural, involving multiple cranial nerves.

    • Implications:

    • Complete surgical resection of chondromas is essential to prevent malignant transformation.
    • Long-term, vigilant patient monitoring post-surgery is critical for early detection of recurrence or progression.
    • This case highlights the potential for chondroma to chondrosarcoma transformation in the intracranial space.