Population-based prevalence of repeated group A beta-hemolytic streptococcal pharyngitis episodes
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Published on: November 16, 2016
Jennifer L St Sauver1, Amy L Weaver, Laura J Orvidas
1Division of Epidemiology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA. stsauver.jennifer@mayo.edu
Insights
Approximately 1% of children aged 4-15 experienced recurrent group A beta-hemolytic streptococcal (GABHS) pharyngitis over three years. This highlights a significant public health concern despite the low prevalence of recurrent GABHS infections.
Area of Science:
- Pediatrics
- Infectious Diseases
- Epidemiology
Background:
- Recurrent group A beta-hemolytic streptococcal (GABHS) pharyngitis poses a challenge in pediatric care.
- Understanding the population-based prevalence of repeated GABHS episodes is crucial for public health management.
Purpose of the Study:
- To determine the 3-year period prevalence of recurrent GABHS pharyngitis in children aged 4 to 15 years.
- To analyze age-specific prevalence rates of repeated GABHS infections.
Main Methods:
- A population-based study was conducted in Rochester, Minn., from 1996 to 1998.
- Identified children (4-15 years) with 3+ GABHS pharyngitis episodes/year, at least 1 month apart, using the Rochester Epidemiology Project.
- Defined GABHS episodes by sore throat with positive rapid strep test or culture.
Main Results:
- 208 children met the criteria for repeated GABHS episodes between 1996 and 1998.
- Approximately 1% of children aged 4-15 experienced recurrent GABHS pharyngitis during the study period.
- Prevalence was higher in younger children (2% in 4-6 years) and lower in older children (0.1% in 13-15 years).
Conclusions:
- A small proportion of children experience recurrent GABHS pharyngitis, but this affects a substantial number at the population level.
- Recurrent GABHS infections are associated with increased healthcare costs.
- Further research is needed to identify strategies for reducing recurrent GABHS episodes and associated costs in children.
Objective:
To define the population-based 3-year period prevalence of repeated group A beta-hemolytic streptococcal (GABHS) pharyngitis episodes in children between 4 and 15 years of age.
Patients And Methods:
Residents of Rochester, Minn (age, 4-15 years), who had 3 or more GABHS pharyngitis episodes In 1 year, at least 1 month apart, between January 1, 1996, and December 31, 1998, were Identified using the resources of the Rochester Epidemiology Project (N=536). Pharyngitis episodes (evidence of a sore throat with or without presence of fever) followed by either a positive rapid streptococcus test result or a positive plate culture test result were considered positive GABHS episodes. Age- and sex-specific prevalence rates were calculated, assuming that all residents 4 to 15 years of age in Rochester during 1996 to 1998 were at risk.
Results:
A total of 208 children met our definition for repeated GABHS episodes between 1996 and 1998 and were included in this study. Approximately 1% of children between the ages of 4 and 15 years experienced repeated GABHS pharyngitis episodes between 1996 and 1998. This estimate increased to approximately 2% among children 4 to 6 years of age and decreased to 0.1% among children 13 to 15 years old.
Conclusion:
A relatively small proportion (1%) of children between 4 and 15 years of age experienced repeated GABHS episodes in a 3-year period; however, this proportion represents a substantial number of children who are affected at the population level. Given the increased costs associated with treating repeated GABHS episodes, further studies are necessary to determine how best to reduce episodes and treatment costs in this age group.
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